International Journal of Trichology International Journal of Trichology
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Year : 2012  |  Volume : 4  |  Issue : 3  |  Page : 176-178

N-acetylcysteine in the treatment of trichotillomania

1 Department of Dermatology and Venereology, Hospital Universitario Virgen Macarena, Seville, Spain
2 Department of Dermatology and Cutaneous Surgery, University of Miami, Miller School of Medicine, FL, USA

Correspondence Address:
Ana Rita Rodrigues-Barata
Department of Dermatology and Venereology, Hospital Universitario Virgen Macarena, Av Dr Fedriani s/n, Sevilha, Espańa
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-7753.100090

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Trichotillomania is as medical condition caused by the patient himself by pulling out of is own hair, resulting in a perceptible hair loss pattern that frequently is associated with other psychiatric processes. Generally has a chronic course in most patients, and a challenging therapeutical management. There are several available options for is treatment, but the clinical response is not satisfactory in many patients. Recently, N-acetylcisteine, a glutamate modulator, has shown efficacy in the treatment of trichotillomania and other compulsive behaviors, and is considered a new alternative in the management of this condition. We describe two patients with trichotillomania successfully treated with N-acetylcysteine. Nevertheless, further studies need to be conducted to establish the appropriate treatment regimen and to evaluate it long-term efficacy in improving this chronic condition.

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