| CASE REPORT |
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| Year : 2014 | Volume
: 6
| Issue : 1 | Page : 25-26 |
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The action of prostaglandins on ciliary hypertrichosis: A case report of pachydermoperiostosis
Fabiana P Zarur, Luiza VF d'Almeida, Anna Beatriz C Novellino, Maria Fernanda DG Reis
Prof. Rubem David Azulay Institute of Dermatology, Santa Casa da Misericordia, Rio de Janeiro, RJ, Brazil
Correspondence Address:
Fabiana P Zarur
203 Guimarães Rosa Street 705, Barra da Tijuca Zipcode: 22793-620, Rio de Janeiro, RJ
Brazil
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0974-7753.136756
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Pachydermoperiostosis or primary hypertropic osteoarthropathy is a rare hereditary disorder that was first described in 1868. It is characterized by digital clubbing, pachydermia (thickening of the facial skin and/or scalp), and periostosis (swelling of periarticular tissue and subperiosteal new bone formation). We report a case of a patient with the complete form of the disease, and with a unique appearance of the hair shaft and eyelashes. The authors propose a possible mechanism to justify the abnormalities observed in the patient's hair shafts regarding the metabolism of prostaglandins and its relationship with the hair follicle physiological cycle. |
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