International Journal of Trichology International Journal of Trichology
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Year : 2016  |  Volume : 8  |  Issue : 1  |  Page : 11-14

Factors associated with premature hair graying in a young Indian population

Department of Dermatology, Hairline International Hair Clinic, Bengaluru, Karnataka, India

Correspondence Address:
Swagata Chakrabarty
Hairline International Hair Clinic, 199, 16th Main Road, 4th ‘T’ Block, Jayanagar, Bengaluru - 560 041, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-7753.179384

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Context: Although the primary cause of premature hair graying (PHG) is considered to be genetic, certain environmental factors also play a role. Trace element deficiencies such as Vitamin B12, Vitamin D3, and calcium may also be associated with PHG. However, India-specific data are relatively sparse. Aims: The present study aimed at identifying factors associated with PHG in Indian patients. Settings and Design: A case–control study was conducted at a trichology clinic in Bengaluru between October 2013 and April 2014 with a total of 37 cases of PHG and 37 age- and gender-matched controls. Materials and Methods: A total of 100 subjects were investigated for various parameters such as hemoglobin, serum ferritin, zinc, copper, calcium, Vitamin B12, and Vitamin D after obtaining informed consent. Statistical Analysis Used: Chi-square test was used to compare proportions between groups. Means were compared between groups using Student's t-test.Results: Serum ferritin levels were lower in patients with PHG as compared to the control group and the differences were statistically significant (P < 0.001). Furthermore, as compared to the controls, patients with PHG had lower serum Vitamin B12 levels (P < 0.001). Individuals with PHG had significantly lower levels of high-density lipoprotein cholesterol (HDL-C) as compared to the control group (P < 0.001). Significant proportions of patients with PHG had a sedentary lifestyle and admitted to having irregular eating habits. Conclusion: PHG is associated with low serum ferritin, Vitamin B12, and HDL-C levels in Indian patients aged <25 years. However, studies with large sample sizes may be required to conclusively define these putative associations.

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