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International Journal of Trichology International Journal of Trichology
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CASE REPORT
Year : 2018  |  Volume : 10  |  Issue : 2  |  Page : 89-91

Nilotinib-induced perforating folliculitis: Two cases


1 Department of Dermatology, Base Hospital Delhi Cantt, New Delhi, India
2 Department of Dermatology, Jorhat Medical College and Hospital, Jorhat, Assam, India

Correspondence Address:
Dr. Debdeep Mitra
Department of Dermatology, Base Hospital Delhi Cantt, New Delhi - 110 010
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijt.ijt_85_17

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Cutaneous adverse effects of chemotherapy are widely known but underreported. A significant advancement is made in the field of oncology with the advent of new classes of drug being added to the existing classes at a fast pace. Most of these cutaneous adverse effects are self-limiting and subsides on suspending the drug either temporarily or permanently. Some of these effects are merely overlooked by the patients and the treating physician hence goes un-noticed. Nilotinib is a newer second-generation tyrosine-kinase inhibitor approved for the management of chronic myeloid leukemia. This drug is rapidly establishing itself as a first-line therapy for chronic myeloid leukemia. Like other chemotherapeutic agents, a wide array of cutaneous adverse effects is noted with this drug. We report two cases of perforating folliculitis induced by nilotinib.


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