International Journal of Trichology International Journal of Trichology
 Print this page Email this page Small font sizeDefault font sizeIncrease font size
  Home | About IJT | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Online submission | Subscribe | Advertise | Contact us | Login   

 Table of Contents  
Year : 2020  |  Volume : 12  |  Issue : 3  |  Page : 137  

A study of association of premature graying of hair and osteopenia in North Indian Population

Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Submission06-May-2020
Date of Decision17-Jul-2020
Date of Acceptance22-Jul-2020
Date of Web Publication14-Aug-2020

Correspondence Address:
Prof. Mahmood Dhahir Al-Mendalawi
P.O.Box 55302, Baghdad Post Office, Baghdad
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijt.ijt_72_20

Rights and Permissions

How to cite this article:
Al-Mendalawi MD. A study of association of premature graying of hair and osteopenia in North Indian Population. Int J Trichol 2020;12:137

How to cite this URL:
Al-Mendalawi MD. A study of association of premature graying of hair and osteopenia in North Indian Population. Int J Trichol [serial online] 2020 [cited 2023 Jan 30];12:137. Available from: https://www.ijtrichology.com/text.asp?2020/12/3/137/292104


I refer to the interesting case–control study published by Agarwal et al.[1] in March–April 2020 issue of the International Journal of Trichology. On using ultrasound bone densitometer to estimate bone mineral density (BMD), the authors compared the grade of osteopenia in individuals with premature graying of hair (PGH) and those without PGH. They found that the mean BMD in the case group was 0.76 ± 1.00 compared to 0.68 ± 1.11 in the control group with no statistically significant difference (P = 0.649).[1] They concluded that was no significant correlation between PGH and steopenia.[1] I presume that due to the following methodological limitation, the study results ought to be cautiously interpreted. In the study methodology, the authors stated that BMD was assessed based on the World Health Organization (WHO) criteria in which T-score of BMD between 1.0 and 2.5 was regarded as osteopenia.[1] The impact of that limitation could be addressed in dual aspects.

First, it is noteworthy that WHO definition criteria of osteopenia using T-scores were introduced in 1994. Certain concerns have been raised on the correctness of the use of the WHO T-score thresholds for defining osteopenia which might be attributed to the inappropriateness of these definition criteria at skeletal sites other than the forearm, hip, and spine, or when other tools, such as quantitative ultrasound are utilized.[2]

Second, it is obvious that BMD normative data (BMDND) are controlled by different determinants, such as age, gender, weight, and race.[3] Based on these determinants, BMDND have been formulated for certain populations to be employed in the researches centers and clinical settings.[4],[5] Since population in India has its unique characteristics, there is a need to construct national BMDND. Employing local standard is expected to yield a better idea on the association between steopenia and PGH.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

   References Top

Agarwal S, Choudhary A, Kumar A, Zaidi A, Mohanty S, Yadav S. A study of association of premature graying of hair and osteopenia in North Indian population. Int J Trichol 2020;12:75-8.  Back to cited text no. 1
  [Full text]  
Knapp KM, Blake GM, Spector TD, Fogelman I. Can the WHO definition of osteoporosis be applied to multi-site axial transmission quantitative ultrasound? Osteoporos Int 2004;15:367-74.  Back to cited text no. 2
Wu Q, Lefante JJ, Rice JC, Magnus JH. Age, race, weight, and gender impact normative values of bone mineral density. Gend Med 2011;8:189-201.  Back to cited text no. 3
Alwis G, Rosengren B, Nilsson JA, Stenevi-Lundgren S, Sundberg M, Sernbo I, et al. Normative calcaneal quantitative ultrasound data as an estimation of skeletal development in Swedish children and adolescents. Calcif Tissue Int 2010;87:493-506.  Back to cited text no. 4
Zhang ZQ, Ho SC, Chen ZQ, Zhang CX, Chen YM. Reference values of bone mineral density and prevalence of osteoporosis in Chinese adults. Osteoporos Int 2014;25:497-507.  Back to cited text no. 5


    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

  In this article

 Article Access Statistics
    PDF Downloaded32    
    Comments [Add]    

Recommend this journal