International Journal of Trichology International Journal of Trichology
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Year : 2021  |  Volume : 13  |  Issue : 6  |  Page : 36-38

Pemphigus vulgaris localized to the scalp with complete response to topical steroids

Department of Dermatology, Principe De Asturias University Hospital, Alcalá De Henares, Spain

Correspondence Address:
David Vega-Diez
Department of Dermatology, Principe De Asturas University Hospital, Carretera De Alcalá-Meco S/N, CP 28805, Alcalá de Henares, Madrid, España
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijt.ijt_95_20

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Pemphigus vulgaris (PV) is an anti-cadherin autoimmune disease, characterized by the production of anti-desmoglein 3 (and to a lesser extent anti-desmoglein 1) antibodies, producing acanthosis, typically suprabasal, which clinically translates into flaccid blisters and erosions, generally starting on mucous membranes, with subsequent appearance of skin lesions. Only about 25 cases of PV of exclusively cutaneous location have been described in the literature. Treatment with potent topical steroids is usually sufficient to control the symptoms. We present the case of a 68-year-old female patient with localized PV in the scalp, presenting as alopecic and scabby plaque, with excellent response and hair regrowth with topical corticotherapy.

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