CASE REPORT
Year : 2012 | Volume
: 4 | Issue : 2 | Page : 93--97
Is Propionibacterium acnes associated with hair casts and alopecia?
Etienne Wang, Joyce Siong-See Lee, Tan Hiok Hee
Department of Dermatology, National Skin Centre, 1 Mandalay Road, Singapore
Correspondence Address:
Etienne Wang
National Skin Centre, 1 Mandalay Road, 308205
Singapore
We report a series of four patients who presented with complaints of diffuse non-scarring alopecia. They had similar clinical features of alopecia, hyperseborrhea, and distinct keratinaceous hair casts that encircled the hair shafts. Propionibacterium acnes was isolated from two of the patients�SQ� scalp, and Gram-positive, Giemsa-positive bacteria were seen in the hair follicles in the scalp biopsy of one of the patients. The patients�SQ� symptoms did not respond to standard treatment for seborrheic dermatitis, but responded to a course of systemic antibiotics targeting P. acnes. We propose a role for P. acnes colonization of the terminal hair follicles in the pathogenesis of hair casts, and possibly diffuse non-scarring alopecia. Possible mechanisms of pathogenesis are discussed with a literature review.
How to cite this article:
Wang E, Lee JS, Hee TH. Is Propionibacterium acnes associated with hair casts and alopecia?.Int J Trichol 2012;4:93-97
|
How to cite this URL:
Wang E, Lee JS, Hee TH. Is Propionibacterium acnes associated with hair casts and alopecia?. Int J Trichol [serial online] 2012 [cited 2023 Jun 6 ];4:93-97
Available from: https://www.ijtrichology.com/article.asp?issn=0974-7753;year=2012;volume=4;issue=2;spage=93;epage=97;aulast=Wang;type=0 |
|
|
|
