International Journal of Trichology International Journal of Trichology
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   2012| April-June  | Volume 4 | Issue 2  
    Online since June 1, 2012

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Pressure alopecia
Kate E Davies, PD Yesudian
April-June 2012, 4(2):64-68
DOI:10.4103/0974-7753.96901  PMID:23180911
Postoperative or pressure alopecia (PA) is an infrequently reported group of scarring and non-scarring alopecias. It has been reported after immobilization of the head during surgery and following prolonged stays on intensive care units, and may be analogous to a healed pressure ulcer. This review presents a summary of cases published in pediatrics and after cardiac, gynecological, abdominal and facial surgeries. PA may manifest as swelling, tenderness, and ulceration of the scalp in the first few postoperative days; in other cases, the alopecia may be the presenting feature with a history of scalp immobilization in the previous four weeks. The condition may cause considerable psychological distress in the long term. Regular head turning schedules and vigilance for the condition should be used as prophylaxis to prevent permanent alopecia. A multi-center study in high-risk patients would be beneficial to shed further light on the etiology of the condition.
  15 7,890 106
Is Propionibacterium acnes associated with hair casts and alopecia?
Etienne Wang, Joyce Siong-See Lee, Tan Hiok Hee
April-June 2012, 4(2):93-97
DOI:10.4103/0974-7753.96907  PMID:23180917
We report a series of four patients who presented with complaints of diffuse non-scarring alopecia. They had similar clinical features of alopecia, hyperseborrhea, and distinct keratinaceous hair casts that encircled the hair shafts. Propionibacterium acnes was isolated from two of the patients' scalp, and Gram-positive, Giemsa-positive bacteria were seen in the hair follicles in the scalp biopsy of one of the patients. The patients' symptoms did not respond to standard treatment for seborrheic dermatitis, but responded to a course of systemic antibiotics targeting P. acnes. We propose a role for P. acnes colonization of the terminal hair follicles in the pathogenesis of hair casts, and possibly diffuse non-scarring alopecia. Possible mechanisms of pathogenesis are discussed with a literature review.
  11 17,681 54
Clinico-investigative profile of patients of hirsutism in a tertiary level institution
Divya Sharma, Vinay Shanker, Gitaram Tegta, Mudita Gupta, Ghanshyam Kumar Verma
April-June 2012, 4(2):69-74
DOI:10.4103/0974-7753.96904  PMID:23180912
Introduction: Hirsutism has a significant impact on the quality of life and serves as a marker of underlying hormonal and systemic conditions. The aim of this study was to study the clinical, biochemical characteristics of these patients and other associations. Materials and Methods: Fifty (n=50) consecutive newly diagnosed patients of hirsutism were assessed during a period from August 2009 to July 2010 using modified Ferriman Gallwey (mF-G) score. Results: Idiopathic hirsutism (IH) was found in 30 (60%) patients followed by polycystic ovarian syndrome (PCOS) in 19 (38%) patients. Other causes included late-onset classic adrenal hyperplasia in two (4%) and hypothyroidism in four (8%) patients. The mean age at presentation was 23.8±6.657 years. Total (T) and free testosterone (fT), 17-hydroxyprogesterone was significantly higher in PCOS than IH. Conclusion: The present data show IH as the commonest cause of hirsutism in our study population. Face, chest, and lower abdomen have a higher impact on the hirsutism score while upper back, abdomen, and lower back are rarely involved.
  6 5,383 132
Pili annulati with fragility: Electron microscopic findings of a case
Gulsen Akoglu, Selma Emre, Ahmet Metin, K Mine Erbil, Demet Akpolat, Aysegul Firat, Murvet Hayran
April-June 2012, 4(2):89-92
DOI:10.4103/0974-7753.96909  PMID:23180916
Pili annulati (PA) is typically characterized by shinny beads seen along the hair shaft. PA is accepted to belong to the classification of hair shaft abnormalities without fragility. Herein, we described a 14-year-old, fair skin with dark-haired girl diagnosed as PA with fragility which was demonstrated by weathering features in electron microscopic examinations. The patient had shinny beaded, easily breakable hairs since the age of four. A few broken hairs were observed by a light pull test. Transmitted light microscopy revealed periodic dark bands in the hair shaft. These dark bands disappeared after application of 10% aqueous potassium hydroxide. Multiple cavities within hair shaft and severe cuticular damages representing the weathering pattern were observed in electron microscopic examinations. All these findings were found to be consistent with presence of fragility in PA. This case provides evidences of fragile hair structure of PA which may be due to pathological cavities within hair shafts.
  3 7,420 45
Multiple firm mobile swellings over the scalp
Keshavmurthy A Adya, Arun C Inamadar, Aparna Palit
April-June 2012, 4(2):98-99
DOI:10.4103/0974-7753.96906  PMID:23180918
  3 5,395 73
Trichoscopy as an aid in the diagnosis of trichotillomania
Jenny Mathew
April-June 2012, 4(2):101-102
DOI:10.4103/0974-7753.96903  PMID:23180920
  3 4,255 77
Silvery grey hair: Clue to diagnose immunodeficiency
MS Sahana, S Sacchidanand, R Hiremagalore, GS Asha
April-June 2012, 4(2):83-85
DOI:10.4103/0974-7753.96910  PMID:23180914
Silvery hair is a common presentation of rare group of autosomal recessive disorders called Silvery hair syndromes including Griscelli syndrome (GS), Chediak-Higashi syndrome, and Elejalde syndrome. GS is characterized by a silvery grey sheen to hair, large clumped melanosomes in hair shaft, partial albinism, and variable cellular immunodeficiency. We report two cases of GS with classical clinical features and confirmatory findings by microscopic skin and hair examination.
  2 8,063 120
Concomitant presentation of alopecia areata in siblings: A rare occurrence
Roshni Menon, CM Kiran
April-June 2012, 4(2):86-88
DOI:10.4103/0974-7753.96911  PMID:23180915
Alopecia areata (AA) is one among the many causes of non-scarring alopecia in children. Family history has been noted in 10-20% of cases, but concomitant presentation in siblings is extremely rare. The patterns and associations of childhood AA are similar to adults; however, there are some differences which are being highlighted in this article.
  1 4,261 53
Sensitive scalp
Kiran Godse, Vijay Zawar
April-June 2012, 4(2):102-104
DOI:10.4103/0974-7753.96905  PMID:23180921
  1 6,025 102
The germinative epithelium of sheep vibrissae and wool follicles has extensive proliferative potential but is dependent on the dermal papilla
Nicholas W Rufaut, Nicole T Goldthorpe, Anthony J Craven, Olivia AM Wallace, Janet E Wildermoth, Allan J Nixon
April-June 2012, 4(2):75-82
DOI:10.4103/0974-7753.96908  PMID:23180913
Aim: To investigate the growth potential of keratinocytes derived from the germinative epithelium (GE) of ovine hair follicles. Stem cells from the outer root sheath (ORS) of hair follicles migrate to the GE in the lower follicle where they proliferate and differentiate to form the hair fiber. It has been suggested that the GE comprises transit-amplifying cells and that the duration of anagen is determined by their limited proliferative potential. However, we show here that keratinocytes derived from the GE of ovine follicles grow extensively in vitro, arguing against this hypothesis. Materials and Methods: Primary cultures of keratinocytes were initiated from microdissected GE tissue from ovine vibrissae and wool follicles. Clonal lines of keratinocytes were derived by limiting dilution. Their growth potential was determined by exhaustive serial passaging. Expression of differentiation markers was evaluated by real-time polymerase chain reaction. Results: Initiation of these cultures required that interaction between the GE and dermal papilla was maintained. However, the keratinocytes could subsequently be cloned and were grown as pure cell populations for 26-52 cell doublings. This proliferative potential is several orders of magnitude greater than required to maintain a single anagen phase. The keratinocytes were indistinguishable from ORS keratinocytes from the same follicles, expressing K14 while undifferentiated, and upregulating the epidermal and inner root sheath markers, loricrin and KRT27 on differentiation. Thus, these cells initially depend on papilla-derived signals to grow, but can revert to an ORS-like phenotype in vitro. Their extensive proliferative capacity shows that the GE is not an exclusively transit-amplifying cell population.
  1 5,023 35
Mind the hair
Patrick Yesudian
April-June 2012, 4(2):61-61
DOI:10.4103/0974-7753.96894  PMID:23180909
  - 3,292 85
Welcome to hair India 2012
S Murugusundram
April-June 2012, 4(2):62-63
DOI:10.4103/0974-7753.96895  PMID:23180910
  - 4,566 118
Comprehending trichotillomania
Dilip Gude, Syed Naveed
April-June 2012, 4(2):100-101
DOI:10.4103/0974-7753.96902  PMID:23180919
  - 3,382 44
16th Annual Meeting of the European Hair Research Society

April-June 2012, 4(2):105-106
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  - 2,854 54
Program Schedule

April-June 2012, 4(2):107-111
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  - 1,372 33
Scientific Abstract Author Index

April-June 2012, 4(2):112-116
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  - 1,366 45
Oral Presentations

April-June 2012, 4(2):117-130
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  - 1,437 76
Poster Presentations

April-June 2012, 4(2):131-152
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  - 1,391 56